GeneFluidics’ sensor technology enables quantification of nucleic acids and proteins in unprocessed samples on a single platform. Our patented sensor fabrication and electrochemical detection methods provide high sensitivity even in unamplified, unpurified biological samples. Results are delivered within 1 hour.
Ultra-sensitive
Sub-femtomolar (genetic material) and sub-pg/mL (protein) sensitivities are made possible by taking advantage of high turnover enzyme cycling.
Multiplexed
A combination of immunoassays and genetic assays can be performed simultaneously on a sensor array.
Versatile
Compatible with most ELISA reagents while providing superior performance.
Simple
Sensors with optical grade flatness block non-specific binding of cellular debris, and thus eliminate the need of purification even for unprocessed biological samples.
Fully automated
Benchtop and portable systems are available which fully automate the assay process.
NEW! GeneFluidics now offers an assay compatibility study service
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- K. E. Mach, R. Mohan, E. J. Baron, M.-C. Shih, V. Gau, P. K. Wong, and J. C. Liao, “A Versatile Biosensor Platform for Rapid Antimicrobial Susceptibility Testing Directly from Clinical Samples”, Journal of Urology 185, 148-153. 2011.
- C. H. Chen, V. Gau, D. D. Zhang, J. C. Liao, Fei-Yue Wang, and P. K. Wong, “Statistical Metamodeling for Revealing Synergistic Antimicrobial Interactions”, PLoS ONE 5, e15472, 2010.
- Chia Hsiang Chen, Yi Lu, Mandy L. Y. Sin, Kathleen E. Mach, Donna D. Zhang, Vincent Gau, Joseph C. Liao, and Pak Kin Wong, “Antimicrobial Susceptibility Testing Using High Surface-to-Volume Ratio Microchannels”, Analytical Chemistry 8, 1012-1019, 2010.
- M. L. Y. Sin, V. Gau, J. C. Liao, and P. K. Wong, “Electrothermal Fluid Manipulation of High-Conductivity Samples for Laboratory Automation Applications”, Journal of Association for Laboratory Automation 15, 426-432, 2010.
- Y. Pan, G. A. Sonn, M. L. Y. Sin, K. E. Mach, M.-C. Shih, V. Gau, P. K. Wong, and J. C. Liao, “Electrochemical Immunosensor Detection of Urinary Lactoferrin in Clinical Samples for Urinary Tract Infection Diagnosis”, Biosensors and Bioelectronics 26, 649-654, 2010.
- May L. Chiu, Walson Lawi, Steven T. Snyder, Pak Kin Wong, Joseph Liao, and Vincent Gau, “Matrix Effects – A Challenge Toward Automation of Molecular Analysis”, Journal of the Association for Laboratory Automation 15, 233-242, 2010.
- Mandy L. Y. Sin, Vincent Gau, Joseph C. Liao, David A. Haake, and Pak Kin Wong, “Active Manipulation of Quantum Dots Using AC Electrokinetics", Journal of Physical Chemistry C 113, 6561-6565, 2009.
- Walson Lawi, Chris Wiita, Steven T. Snyder, Fang Wei, avid Wong, Pak Kin Wong, Joseph C. Liao, David Haake, Vincent Gau, “A Microfluidic Cartridge System for Multiplexed Clinical Analysis”, Journal of the Association for Laboratory Automation 14, 407-412, 2009.
- Vincent Gau, Shu-Ching Ma, Hua Wang, Joni Tsukuda, John Kibler, and David A. Haake “Electrochemical molecular analysis without nucleic acid amplification. Methods 37, 73-83, 2005.
- J. C. Liao, M. Mastali, V. Gau, M. A. Suchard, A. K. Møller, D. A. Bruckner, J. T. Babbitt, Y. Li , J. Gornbein, E. M. Landaw, E. R. McCabe, B. M. Churchill, D. A. Haake, "Use of electrochemical DNA biosensors for rapid molecular identification of uropathogens in clinical urine specimens." J Clin Microbiol 44: 2: 561-70, 2006.
- J. C. Liao, Y. Ma, Y. Li, V. Gau, M. Mastali, C-P Sun, E. R. B. McCabe, E. M. Landaw, D.A. Haake, B. M. Churchill, C.-M. Ho, "A point-of-care micro-laboratory for direct pathogen identification in body fluids" IEEE NTC Review on Advances of Micro, Nano, and Molecular Systems, 1109-1112, 2006.
- C. P. Sun, J. C. Liao, Y. H. Zhang, V. Gau, M. Mastali, J. T. Babbitt, W. S. Grundfest, B. M. Churchill, E. R. McCabe, D. A. Haake "Rapid, species-specific detection of uropathogen 16S rDNA and rRNA at ambient temperature by dot-blot hybridization and an electrochemical sensor array." Mol Genet Metab 84, 90-9, 2005.
- V. Gau, D. Wong, “Oral Fluid Nanosensor Test (OFNASET) with advanced electrochemical-based molecular analysis platform.” Ann NY Acad Sci 1098, 401-410, 2007.
- W. Fang, J. Wang, W. Liao, B. G. Zimmermann, D. Wong, C.-H. Ho, “Electrochemical detection of low-copy number salivary RNA based on specific signal amplification with a hairpin probe,” Nucleic Acids Res. 36, e65, 2008.
